Cognitive decline in patients with essential tremor

Essential tremor (ET) is a heterogeneous disease with high prevalence and disability. Traditionally, the was considered benign presence of tremor, severity which increases during observation period. The trembling varies widely from mild, not requiring therapy, to disabling. That making difficulties assess disease. However, disability in patients ET can occur only due tremor.The underestimated side disease, despite long history study, remains non-motor manifestations, including cognitive decline. Cognitive decline essential compared general population, has greater risk transformation into dementia. In ET, comparison other domains, executive functions are predominantly affected. Patients also characterized by low awareness concern about changes intelligence. study brain using voxel morphometry, group that contradict each revealed. Most often, change density cortex different parts detected control group. most affected area precuneus. This may explain dysfunction highlight likely neurodegenerative nature tremor. absence preventive incidence intelligence emphasizes need for close monitoring patients.